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　　Zhongxin Jingwei, July 12 (Lin Yusi) With the increasing demand for HPV vaccine, the demand for HPV vaccine is in short supply due to limited production capacity, especially the nine-valent vaccine "one vaccine is hard to find", which makes many women who seek seedlings miss the best vaccination age.

　　Under this circumstance, recently, in some areas, the voice of "Nine-valent vaccine is about to relax the age limit to 45 years old" appeared. So, is it realistic to "age-extend" the nine-valent vaccine? How long will it take to achieve it?

　　Photo courtesy of nine-valent vaccine packaging box respondents

　　"selling contract packages" and "distributing goods" to sell nine-valent HPV vaccines

　　Cervical cancer is mainly caused by human papillomavirus (HPV). Wu Tao, an attending physician in the Department of Gynecology and Oncology of Shaanxi Cancer Hospital, told Zhongxin Jingwei that there are more than 100 kinds of HPV viruses, which are divided into high-risk and low-risk types. The common high-risk HPV types in China include 16, 18, 31, 33, 45, 52 and 58. Women who usually have sex may be infected with HPV virus, but most of them are transient infections. Like a cold, the body’s resistance is normal, and most of them can turn the virus negative by relying on their own immunity within one year. However, a small number of people with persistent high-risk human papillomavirus infection (generally believed to be more than one year) will lead to cervical precancerous lesions, which will continue to develop and even progress to cervical cancer.

　　However, cervical cancer can also be prevented, and the incidence of cervical cancer and precancerous lesions will be significantly reduced by vaccinating HPV vaccine among school-age women.

　　According to the annual report of Wan Tai Biology in 2021, according to the data of vaccine signing and wholesale by the Central Inspection Institute and local inspection institutes, from the perspective of large varieties, 181 batches of bivalent HPV vaccines were signed and wholesale, up by 269% year-on-year, and 44 batches of nine-valent HPV vaccines were issued, up by 83% year-on-year.

　　Even so, the nine-valent HPV vaccine is still "one seedling is hard to find" and even more sales tricks appear.

　　Recently, according to media reports, HPV vaccine needs to be "distributed", that is, with other vaccines or physical examinations, in order to get an HPV vaccine. A scalper who can help make an appointment for a nine-valent HPV vaccine told Zhongxin Jingwei that some hospitals have the situation of "selling contract packages", that is, compulsory physical examination, charging extra fees and bringing some profits to hospitals.

　　In addition, the scalper also revealed that because there are too many people who need to be vaccinated, releasing seedlings will never satisfy the market. In addition to releasing seedlings, some hospitals will buy and sell seedlings. The scalper said that he can help to make an appointment for the nine-valent seedlings by paying another 2,000 yuan, and he can make an appointment in about two weeks at the earliest. "All three needles can be made, and there is no need to renew the appointment. The needles are really nine-valent seedlings, and the traceability code on the box can be scanned to check the authenticity."

　　Nine-valent vaccination card in the new Jingwei Lin Yusi photo

　　Faced with the situation that the domestic HPV vaccine market is in short supply, there are also criminals who profit from smuggling nine-valent HPV vaccines at low prices. Recently, Liuzhou Intermediate People’s Court of Guangxi issued a first-instance verdict on a case of smuggling nine-valent cervical cancer vaccine. The defendant Xu Moli and other four people bought vaccines from Hong Kong at a low price and smuggled them to Shenzhen, and then sold them to various places. Four people smuggled 2,824 vaccines, involving nearly 3 million yuan, with a total profit of more than 120,000 yuan.

　　In fact, it is really helpless for people to turn to the yellow cattle to make an appointment and be asked by the hospital to "distribute" the seedlings. The way to make an appointment for HPV vaccines in various places is harsh, and it has been a long time since they were unable to "go ashore" for many years. Zhongxin Jingwei learned that Beijing made an appointment online and by telephone. However, many community hospitals have told Zhongxin Jingwei that the nine-valent HPV vaccine has no seedlings, and I don’t know when it will be available. Some hospitals in Beijing also have household registration restrictions, and people outside the jurisdiction are not allowed to vaccinate.

　　There are also areas such as Shenzhen that decide who can be vaccinated by "shaking the number". Many people have reported to Zhongxin Jingwei that the process of shaking the number is time-consuming and labor-intensive, and the speed of fighting hands is also luck. Many people can’t get it for half a year. Even if they can get it, there is no guarantee that the other two needles can be vaccinated on time, and there may be problems of overage.

　　Why is the nine-valent HPV vaccine still "one vaccine is hard to find"?

　　It is understood that there are currently three kinds of HPV vaccines listed in the world, and the number of HPV virus subtypes is different, including bivalent vaccine, tetravalent vaccine and nonavalent vaccine. Five HPV vaccine products have been approved for marketing in China, including three imported HPV vaccines and two domestic HPV vaccines.

　　In 2006, the world’s first HPV vaccine came out, until 2016, the first HPV vaccine approved for marketing in China — — The bivalent HPV vaccine "sirrah Shi" produced by GlaxoSmithKline has been in a blank period in China for ten years.

　　Luo Ling, the fund manager of Shanghai Congrong Investment Management Co., Ltd., said in an interview with Zhongxin Jingwei that the reason for the current strong demand is that many people have not been vaccinated with HPV before, and the demand has accumulated to be released at this stage. The next 5 to 10 years may be the stage of replanting the stock population, followed by the annual vaccination of the new population.

　　In 2018, the U.S. Merck nine-valent HPV vaccine "Jiadaxiu" was listed in mainland China, and Zhifei Bio became the exclusive agent of Merck HPV vaccine in China. However, up to now, the nine-valent HPV vaccine is still hard to find.

　　Behind the lack of seedlings, there is only one nine-valent vaccine manufacturer in Merck. Recently, Tian Anna, president of Merck China, pointed out in an interview with the media that it takes nearly four years for each dose of HPV vaccine to be produced and applied.

　　However, the supply of nine-valent HPV vaccine has also increased accordingly. Recently, Zhifei Bio said on the interactive platform that in the first quarter of 2022, the number of batches of nine-valent HPV vaccines increased by nearly 280% year-on-year.

　　Wu Tao said that vaccination with HPV vaccine is the best way to prevent HPV infection and cervical cancer, but don’t blindly wait and pursue the most expensive vaccine, but should be protected as soon as possible. If there is no nine-valent HPV vaccine, it is a better choice to vaccinate low-priced HPV vaccine.

　　In addition to the nine-valent HPV vaccine, the four-valent HPV vaccine market is currently in the hands of Merck. It is understood that the whole vaccination cost of tetravalent and nine-valent vaccines is 2394 yuan and 3894 yuan respectively. In the market competition of bivalent vaccine, domestic vaccine also gets a share with its price advantage.

　　In 2020, Wan Tai Bio’s bivalent HPV vaccine "Xinkening" went on the market, and one shot was only 329 yuan. Even if it was inoculated with three shots, it was only 987 yuan, far lower than the 1,740 yuan of the same dose of GlaxoSmithKline "sirrah Shi".

　　As the first domestic HPV vaccine, "Xinkening" adopts the research and development route of Escherichia coli technology, with low cost and high efficiency. According to the 2021 annual report, the biological business income of Wan Tai increased by 144.25%, mainly due to the increase of bivalent HPV vaccine, reagents and active raw materials, and the gross profit margin of vaccine business was as high as 92.55%. In 2021, the sales of bivalent HPV vaccine in Wan Tai exceeded 10 million, and the government procurement accounted for only 1.5%.

　　In March, 2022, watson biological bivalent HPV vaccine "Wozehui" was also approved for listing, and it was officially put on the market at the end of May, taking away part of the biological market in Wan Tai at a lower price.

　　At the end of May this year, the bivalent HPV vaccine of watson biological and Wanbiotai jointly won the bid for the procurement project of Jiangsu provincial government. The total purchase quantity is 32,000 pieces, of which 22,400 pieces were won at the proposed bid price of 246 yuan/piece in watson biological and 329 yuan/piece in Wan Tai Bio, only 9,600 pieces were won.

　　In this regard, Wan Tai Bio said that since its listing, its bivalent HPV vaccine has been mainly supplied to the self-funded market, and the purchase of free voluntary vaccination by local governments for specific age groups is relatively small, which has limited impact on the company’s operating income.

　　However, Wu Tao told Zhongxin Jingwei that there are regional differences in the distribution of cervical cancer in China, mainly concentrated in the central and western regions, and rural areas are highly prevalent in cities. Clinically, patients with advanced cervical cancer are mostly from rural areas. There are hundreds of millions of low-and middle-income women in China, who are concerned about the price of HPV vaccine besides the preventive effect and safety. "For economically underdeveloped people, the price will directly affect the choice of HPV vaccine types."

　　Is it close to relaxing the age limit?

　　On the track of nine-valent HPV vaccine, which is in short supply, there are more and more R&D and production enterprises in China. It is worth noting that some domestic nine-valent vaccines are expanding the age of the experimental population compared with the suitable age of 16 to 26 years approved by Merck nine-valent vaccine in Chinese mainland.

　　This may mean that with the listing of more nine-valent HPV vaccines in the future, not only can the situation of "one vaccine is hard to find" be alleviated, but the waiting school-age women do not have to be anxious because they are over 26 years old.

　　It is understood that Chongqing Bowei Baitai Biopharmaceutical Co., Ltd. (hereinafter referred to as Bowei Bio), Jiangsu Ruike Biotechnology Co., Ltd. (hereinafter referred to as Ruike Bio), Beijing Kangle Guardian Biotechnology Co., Ltd. and Wan Tai Bio’s nine-valent HPV vaccine have all entered the third clinical stage.

　　Wan Tai Bio started the Phase III clinical trial in September 2020. At that time, the company said that the phase III clinical trial of the nine-valent vaccine was aimed at evaluating the effectiveness and safety of the vaccine in female healthy volunteers aged 18-45. However, as early as 2020, Wan Tai Bio said that the nine-valent vaccine is not expected to be listed within three years according to clinical experience.

　　According to the information of National Medical Products Administration Drug Evaluation Center, the phase III clinical trial of nine-valent vaccine announced by Bowei Bio in 2020 also aims to evaluate the immunogenicity and safety of HPV vaccine among women aged 20-45 in China. Phase III clinical trial was completed in September 2021.

　　In June, 2021, Ruike Bio announced the effectiveness and safety of its nine-valent vaccine in the phase III clinical trial of healthy women, one of the purposes of which was to evaluate the safety and immunogenicity of three doses inoculated in healthy women aged 9-17, 16-26 and 18-45. However, the company did not disclose the completion date of the test.

　　Tao Lina, a vaccine expert, said in an interview with Zhongxin Jingwei that the duration of the third phase clinical trial needs to refer to the sample size: the larger the sample size and the higher the cost, the shorter the observation time; The smaller the sample size, the longer the observation time. You can’t have both fish and bear’s paw, with a large sample size and high investment. It will take one or two years to observe the third-phase clinical trial before you can see the significant difference between the vaccine group and the placebo group. The sample size is small, and it may take more than five or six years to get the difference of incidence and summarize it. It will take at least 2 to 6 years from the start of the third phase clinical trial of domestic HPV vaccine to the approval and listing.

　　Wu Tao told Zhongxin Jingwei that in 2019, Merck launched the third phase clinical trial of nine-valent HPV vaccine in China, bridging the immunogenicity and immune persistence test. The observation period is five years, that is, the earliest nine-valent HPV vaccine in China may relax the age limit to 45-year-old women by 2024. Men’s enrollment is also under way. However, if men in China want to get the nine-valent vaccine, they have to wait five years at the earliest.

　　However, Taulina also pointed out that relaxing to the age of 45 also means that more people are snapping up the nine-valent vaccine, which is still difficult to alleviate the situation of "one needle is hard to find" and even more intense. (Zhongxin Jingwei APP)

　　(The opinions in this article are for reference only, and do not constitute investment advice. Investment is risky, so you should be cautious when entering the market. )

Under the tide of new energy, I believe that many friends have replaced their cars with pure electric models. Indeed, unlimited travel, low car costs, and comfortable driving experience make people immersed in it, but the inability to cope with long-distance and inconvenient refueling cause mileage anxiety, which are also practical problems, which are torn. In fact, for friends who want to enjoy various related conveniences of pure electric models and are afraid of mileage anxiety, various manufacturers are currently promoting new plug-in hybrid/range-extended electric models, which is a more balanced choice at present. This time, we are in the budget range of the most mainstream new energy model purchase, and we bring you three models that can refuse mileage anxiety. BYD Frigate 07, Geely Xingyue L Range Extended Electric Edition, and AITO Ask the World M5 to find out.

From the debut to the listing, the BYD Frigate 07 can be said to have been preheated for a long time. As a new medium-sized SUV of BYD Ocean Network, the popularity of the Frigate 07 goes without saying. The new design style, the full series of large 5-seat layouts, and the DM-i/DM-P plug-in hybrid system are added. This is not a wrong choice. The Xingyue L Extended Range Electric Edition has three driving modes: Extended Range, Pure Electric, and Hybrid. It is a veritable all-round player. In the Extended Range Mode, the WLTC service life of the Xingyue L Extended Range Electric Edition can reach 1250km, and there will be no mileage anxiety at all. AITO Qinjie M5 has become a dark horse player among new forces with its Hongmeng cockpit. As a new energy model with a mature range-extending power system, excellent driving experience, and a leading intelligent cockpit experience, the Q-5 is worth looking forward to.

Appearance: Different styles to meet different aesthetics

At the design level, the three cars show a completely different design tone. The frigate 07 adopts the new style of BYD Ocean Network. The new ripple-type center net, sharp light set and BYD’s luminous LOGO show a new look different from the previous BYD, with an excellent sense of novelty; the Xingyue L Extended Range Electric Edition is a "good man at home" style, with straight lines and smooth contours, giving people a reliable and practical sense of vision, which belongs to the traditional aesthetic good-looking; the M5 is a typical sports style, with very smooth lines in the front body, and the overall visual center of gravity is low, and the posture is moving.

In the rear part of the car, the three cars use the current popular through-type light group at the same time. The design details of the frigate 07 light group are innovative, and the swirling structure of the waves on both sides can show the effect of welcoming light when the vehicle is unlocked. With the connecting guide tail above, it is full of personality and recognition; the overall rear of the Xingyue L range-extended electric version is still a stable image of Fangzheng, and under the integration of the slender light strip, it does not appear dull; the rear part of the M5 is still round and full, but the design is relatively ordinary, and there is no obvious recognition.

Although the three cars were positioned differently, it was not difficult to see that the size and body were not very different, and they were almost the same level. This showed that the Star L extended range electric version was a bit low in positioning and misplaced in competition. In fact, due to differences in design, the Q M5 had the smallest sense of visual volume among the three cars, but in terms of intuitively affecting the wheelbase of the driving space, it was the most advantageous one among the three cars.

In terms of tire specifications, the frigate 07 uses 20-inch wheels, while the Star L Extended Range Electric Edition and the M5 both use the mainstream 19-inch wheels of the same class, larger size wheels and the most advantageous body length and height. The visual effect of the frigate 07 is undoubtedly more atmospheric.

The three cars are all models priced 200,000 or more by Chinese brands. There is no need to worry about the basic configuration level. Everything is available, but there are differences in details. Specifically, on the keyless entry and multi-layer sound insulation glass with high daily practicality, the performance of the M5 is relatively strong. The other two cars are only equipped with the function of the front row. It is standard in the whole car and has obvious advantages. In addition, for a medium-sized SUV with a small size, the induction trunk is a configuration that can obviously improve the convenience. Among the three cars, only the frigate 07 is not equipped, and the daily experience is different.

Interior: Technological atmosphere

At the interior level, most of the functions and operations in the three cars are integrated into the central control large screen, creating a strong technological atmosphere. The frigate 07 and the interrogator M5 use a central control floating large screen design, while the Xingyue L is a cross-screen design. Among them, the Xingyue L is uniquely equipped with a co-pilot entertainment screen, which allows the co-pilot passengers to spend time better during long-distance journeys.

In addition, the lining materials of the three cars are very high-grade, and a large area of soft leather wrapping is a common feature. However, for the trend of air conditioning, electronic shift lever and speaker shape, Xingyue L Extended Range Electric Edition and Qjie M5 are too flat, while Frigate 07 is obviously more design sense.

In terms of interior configuration, the performance of the three cars is satisfactory, reflecting the configuration level of a Chinese brand SUV priced at more than 200,000. Specifically, in terms of comfort configuration that everyone cares about, the M5 is better than the M5. The rear seat heating, 15-speaker audio, and 128-color ambient lights are all unique configurations. It is also the only model among the three cars to provide seat massage options, maintaining a leading position in the three dimensions of touch, hearing and vision. Xingyue L Extended Range Electric Edition and Frigate 07 come and go, regardless of height.

At the level of intelligent configuration, all three cars have performed well. The frigate 07 still adopts the standard solution of BYD’s smart cockpit, with a rotating large screen and high-speed 5G network, which can provide an excellent human-machine interaction experience; the Xingyue L extended-range electric version has a solid "stacking material", Qualcomm 8155 chip + three-screen interconnection, and every passenger in the front row can enjoy a rich experience of scientific and technological functions; the main selling point of the M5 is the Hongmeng cockpit. Hongmeng’s strong ecosystem and convenient interaction pattern are very attractive. Overall, the Xingyue L extended-range electric version is still slightly better. After all, with an extra large screen, the satisfaction of the passenger riding experience in the car is also more complete.

Performance: Meet daily use and solve mileage anxiety

The three new energy models can be divided into two technical routes in terms of power system. The Frigate 07 and the Xingyue L extended-range electric version use a plug-in hybrid system, while the Qinjie M5 is an extended-range power. The power performance of the three vehicles is completely no problem for daily household use, and the combination of oil and electricity can achieve a relatively exaggerated value, which has obvious advantages over pure electric vehicles and fuel vehicles.

The M5 is the only model with a rear-mounted rear-drive layout among the three cars. Coupled with a more powerful motor, it will have an advantage in terms of driving pleasure among the three cars. The Star L Extended Range Electric Edition can achieve seamless switching of three driving modes: pure electric, extended range, and plug-in through the three-speed DHT gearbox. Its pure electric cruising range is also the longest among the three cars, and the fuel economy during the use of the car is better. The DM-i system of the Frigate 07 is more standard in all aspects.

Space: There are differences in experience

In terms of riding space, the wheelbase of the three cars is more than 2.8 meters, and it is a large five-seat layout. Specifically, the 1.78-meter-tall experiencer enters the rear row of the Xingyue L Extended Range Electric Edition and the Q World M5 respectively (the front row is his driving position), with two punches and one punch and three fingers respectively, and the head space is more than one punch; the 1.8-meter-tall experiencer enters the rear row of the frigate 07, and there is still more than two punches in the legs, and the head space is also more than one punch. Overall, the rear row of the three cars can leave a relatively ample space for passengers, with the frigate performing the best, while the longest wheelbase of the three cars, the Q World M5, lags behind in the rear legroom, which makes some differences.

In terms of trunk space, the interior of the three models is relatively regular, among which the wheel arch of the frigate 07 is more obvious, and the lateral space is limited. In terms of expansibility, the rear seats of the three cars all support 4/6 ratio reclining, and after reclining, they can form a flat state with the trunk floor, and the load capacity is satisfactory. In addition, the three cars are equipped with electric tailgates, of which only the frigate 07 does not support induction opening, and the convenience in daily use is not as good as that of the Xingyue L Extended Range Electric Edition and the Q-Realm M5.

Security: All are equipped with rich active security configurations

As the commonality of "electric shock" models, all three cars have a wealth of active safety configurations, including rare door opening warning and forward collision warning, which can maximize safety protection regardless of driving or parking. Specifically, there are only a small number of configuration differences in the three cars, among which the most abundant is the Xingyue L Extended Range Electric Edition, which is only not equipped with fatigue driving function, and other aspects are almost at the level of filling the configuration table; while the performance of the Frigate 07 and the M5 is similar, slightly inferior to the Xingyue L when the price is similar.

Summarize:It can be found that although the core satisfaction of the three new energy SUVs recommended this time is to solve mileage anxiety, their respective characteristics are still very clear, and they will not be a moderate experience at all. The AITO M5 is a very obvious sports orientation, including power layout, performance and design style, which is very suitable for users who have certain requirements for control; if you have extreme requirements for fuel consumption and battery life, then the Geely Xingyue L range-extended electric version that seamlessly switches three power modes meets your needs; the DM-i system is very mature and has excellent user word-of-mouth feedback. The BYD Frigate 07 is the choice to ensure that there will be no mistakes. Combined with your own car needs and brand preferences, I believe you can find your favorite car.

　　　 A few days ago, the ancient costume legendary war masterpiece directed by Chen Xunqi exposed the behind- the-scene video of Yang Zongbao (played by Ren Xianqi), the only strong member of the Yang family, and reproduced the scene of the heroic battle of the Yang family general. Going behind the scenes, Ren Xianqi carefully analyzed Yang Zongbao’s character characteristics, and director Chen Xunqi also said that "Ren Xianqi has grasped the essence of Yang Zongbao’s god of war".

Yang Zongbao behind- the-scene video exposure, leading troops into battle

　　　 As the only strong man in the film, Yang Zongbao is under heavy pressure as the main story of the film "Yang Family Women General" is adapted from the classic part of "Twelve Widows’ Journey to the West".

　　　 Unlike the female generals who were on standby in danger, as the leader of the Yang family, in the face of internal and external troubles, Yang Zongbao led the troops into battle and did his best to reverse the war. The video of the bed-the-scene exposed this time opened with Yang Zongbao’s impassioned sentence "Even if a soldier dies in battle, he must move forward bravely". In a short few minutes, it basically showed the fighting scenes or war scenes shot by Ren Xianqi in different scenes. Director Chen Chengqi also explained that "almost all of Yang Zongbao’s scenes are related to’fighting ‘. On the battlefield, he was heroic, and off the battlefield, he called for a marriage with Mu Guiying."

Ren Xianqi interprets "God of War" and joins hands with Cecilia Cheung to go to the battlefield

　　　 Judging from the stills and trailers exposed earlier, the Yang family is very skilled. Whether it is the might of the uniformed leader or the chic practice of the plain clothes, the stories of the generals of the Yang family have been passed down to this day, and they have also become a major attraction in the film.

　　　 The bed-the-scene video revealed this time shows the front and back scenes of Ren Xianqi’s shooting. When talking about the plot of the martial arts, Ren Xianqi analyzed that "the Yang family will use the Yang family gun, which is a long weapon. Its range is larger than that of close combat, and there will be targeted training before. But when you really shoot, you will put on the armor, and the joints will be very restricted, so you need to do more practice." Regarding the choice of characters, Director Chen said that "Yang Zongbao is the god of war in the Yang family, which can bring a lot of honor to the Yang family. Ren Xianqi gave me a feeling of not only elegance, but also roughness. At that time, his sentence’I must do my best ‘made me feel that Yang Zongbao was Ren Xianqi."

　　　 In the exposed behind- the-scene video, there are also several interactive scenes between Ren Xianqi and Cecilia Cheung, and in the trailer, Cecilia Cheung leads the battle, which makes people think about the plot.

Next page More exciting stills

　　With the arrival of 24:00 on June 18, JD.com 618 ended successfully. Many consumers started their favorite mobile phone products during the 618 period, and major mobile phone brands also ushered in comprehensive growth. Data show that during the JD.com 618 period, the iPhone turnover exceeded 10 billion; Xiaomi, Huawei, Honor, iQOO, OPPO, OnePlus, vivo, Samsung, realme, Meizu, Red Devil, Nubia and other brands exceeded 60 mobile phone single product turnover exceeded 100 million. JD.com 618 mobile phone racing list The competition between the brands is also fierce, and the final results have been officially released. Now let’s see what achievements each brand and model has achieved.

　　Looking at the brand situation first, it can be found from the cumulative list of all brand sales that Apple still holds the first place, Xiaomi follows closely, occupying the second position, Honor becomes the third place on the list, vivo/iQOO, Huawei, OPPO/OnePlus, True Me, Samsung, Meizu, and Tianyu also enter the top ten. Looking at the cumulative list of all brand sales, Apple and Xiaomi firmly occupy the top two, while Huawei comes to the third place. Compared with the cumulative list of all brand sales, Nubia enters the top ten positions in the cumulative list of all brand sales.

　　After reading the situation of the brand, let’s take a look at the situation of the single product list. On the cumulative list of all single products, iPhone 15 Pro Max, iPhone 15 Pro, Redmi K70 are deeply loved by consumers and become the TOP3 of the list. After that, iPhone 15, Honor X50, OnePlus Ace 3, Redmi K70E, Xiaomi 13, Redmi Note13 Pro, iQOO Neo9 occupy the fourth to tenth positions. Due to the fact that many consumers adhere to the principle of "buying new and not buying old", the competition for new mobile phones is also extremely fierce. The top of the new mobile phone cumulative list is the iQOO Z9 Turbo, iQOO Neo9S Pro, iQOO Z9, and iQOO Z9x. The three iQOO mobile phones entered the top ten of the new mobile phone cumulative list; HUAWEI Pura 70 became the second largest new mobile phone cumulative list, and HUAWEI Pura 70 Pro + also entered the top ten, occupying the ninth place. In addition, the OPPO Reno12 and Honor 200 released in late May both entered the top ten of the new mobile phone cumulative list.

　　AI mobile phones and folding screen mobile phones have also attracted much attention from consumers. They also achieved good results in JD.com 618, and the sales of folding screen mobile phones increased by more than 100% year-on-year. From the cumulative list of AI mobile phones, it can be found that Redmi K70 and Xiaomi Mi 14 occupy the top two positions, and OnePlus Ace 3, iQOO 12, and Xiaomi Mi 13 all enter the top five of the list. They are all reliable AI mobile phone products. In the cumulative list of large folding screen mobile phones, vivo X Fold3 firmly ranked first, vivo X Fold3 Pro also achieved good results in third place, Huawei Mate X5 occupied second place, and Xiaomi, Honor, OPPO, and Samsung’s large folding screen mobile phones also made the list. In the cumulative list of small folding screen mobile phones, Huawei Pocket 2 took the first place, the newly released Honor Magic V Flip took the second place, and the third place was won by OPPO Find N3 Flip.

　　This year, JD.com 618 brings consumers a "cheap and good" mobile phone consumption experience. In the future, we will continue to work with brands to bring new mobile phones to consumers as soon as possible, so that consumers can enjoy great benefits and high-quality services when purchasing.