标签： 南京夜生活娱乐

Central Meteorological Observatory： Heavy rain and strong convection warning are all in full swing, and the high temperature tolerance in Huanghuai and other places in North China is full.

　　Cctv newsAccording to the Central Meteorological Observatory, yesterday, heavy rainfall mainly occurred in eastern Sichuan, northwestern and southwestern Shaanxi, central Shanxi, northeastern Shandong, central Guangxi, eastern Guangdong and other places, including Chengdu, Mianyang and Guangyuan in Sichuan, Hanzhong in Shaanxi, Baise in Guangxi and Shanwei in Guangdong. Thunderstorms or hailstorms occurred in southern Ningxia, north-central Shaanxi, western Shanxi, and central and eastern Shandong. It is estimated that there will be heavy rain or rainstorm in the southwestern Shaanxi, eastern Sichuan Basin, Jianghan, Jianghuai, northern Jiangnan, eastern Huanghuai, eastern North China, southern Liaoning and northern Heilongjiang on the 28th to 30th, with local heavy rain accompanied by obvious strong convective weather. The Central Meteorological Observatory continued to issue a blue warning for heavy rain and strong convective weather this morning.

　　Today, there are heavy rainstorms in Liaodong Peninsula, eastern Beijing, northern Tianjin, northeastern Hebei, central and eastern Shandong, eastern Sichuan, southwestern Shaanxi, most of Chongqing and western Hubei, among which there is heavy rain (100-140 mm) in northern Chongqing, accompanied by short-term heavy rainfall (the maximum hourly rainfall is 30-50 mm, and the local area can exceed 60 mm). Parts of northeastern Inner Mongolia, southwestern Heilongjiang, central and western Jilin, southern Liaoning, southeastern Shaanxi, eastern Hebei, eastern Beijing, Tianjin, northern and eastern Shandong, northern Anhui, northern Jiangsu and other places will have 8-10 thunderstorms or hail weather, and the local wind can reach 11.

　　The public should pay attention to the weather in time, prevent the adverse effects of heavy rainfall and local strong convective weather on traffic travel, and stay away from areas with high risk of meteorological disasters.

　　In addition, it is expected that there will still be many hot weather in North China, Huanghuai and other places in the next two weeks, with the main high temperature periods from June 29 to July 2 and July 6-10. The daily maximum temperature in central Inner Mongolia, North China, Huanghuai and Fenwei Plain will be 35℃ ~ 39℃, and the local temperature can reach 41℃. High temperature weather is full of endurance, so the public should pay attention to temperature changes, reduce outdoor activities, take measures to prevent heatstroke and heat stroke.

Nine-valent HPV vaccine is ＂one vaccine is hard to find＂. Can relaxing the age limit alleviate it？

　　Zhongxin Jingwei, July 12 (Lin Yusi) With the increasing demand for HPV vaccine, the demand for HPV vaccine is in short supply due to limited production capacity, especially the nine-valent vaccine "one vaccine is hard to find", which makes many women who seek seedlings miss the best vaccination age.

　　Under this circumstance, recently, in some areas, the voice of "Nine-valent vaccine is about to relax the age limit to 45 years old" appeared. So, is it realistic to "age-extend" the nine-valent vaccine? How long will it take to achieve it?

　　Photo courtesy of nine-valent vaccine packaging box respondents

　　"selling contract packages" and "distributing goods" to sell nine-valent HPV vaccines

　　Cervical cancer is mainly caused by human papillomavirus (HPV). Wu Tao, an attending physician in the Department of Gynecology and Oncology of Shaanxi Cancer Hospital, told Zhongxin Jingwei that there are more than 100 kinds of HPV viruses, which are divided into high-risk and low-risk types. The common high-risk HPV types in China include 16, 18, 31, 33, 45, 52 and 58. Women who usually have sex may be infected with HPV virus, but most of them are transient infections. Like a cold, the body’s resistance is normal, and most of them can turn the virus negative by relying on their own immunity within one year. However, a small number of people with persistent high-risk human papillomavirus infection (generally believed to be more than one year) will lead to cervical precancerous lesions, which will continue to develop and even progress to cervical cancer.

　　However, cervical cancer can also be prevented, and the incidence of cervical cancer and precancerous lesions will be significantly reduced by vaccinating HPV vaccine among school-age women.

　　According to the annual report of Wan Tai Biology in 2021, according to the data of vaccine signing and wholesale by the Central Inspection Institute and local inspection institutes, from the perspective of large varieties, 181 batches of bivalent HPV vaccines were signed and wholesale, up by 269% year-on-year, and 44 batches of nine-valent HPV vaccines were issued, up by 83% year-on-year.

　　Even so, the nine-valent HPV vaccine is still "one seedling is hard to find" and even more sales tricks appear.

　　Recently, according to media reports, HPV vaccine needs to be "distributed", that is, with other vaccines or physical examinations, in order to get an HPV vaccine. A scalper who can help make an appointment for a nine-valent HPV vaccine told Zhongxin Jingwei that some hospitals have the situation of "selling contract packages", that is, compulsory physical examination, charging extra fees and bringing some profits to hospitals.

　　In addition, the scalper also revealed that because there are too many people who need to be vaccinated, releasing seedlings will never satisfy the market. In addition to releasing seedlings, some hospitals will buy and sell seedlings. The scalper said that he can help to make an appointment for the nine-valent seedlings by paying another 2,000 yuan, and he can make an appointment in about two weeks at the earliest. "All three needles can be made, and there is no need to renew the appointment. The needles are really nine-valent seedlings, and the traceability code on the box can be scanned to check the authenticity."

　　Nine-valent vaccination card in the new Jingwei Lin Yusi photo

　　Faced with the situation that the domestic HPV vaccine market is in short supply, there are also criminals who profit from smuggling nine-valent HPV vaccines at low prices. Recently, Liuzhou Intermediate People’s Court of Guangxi issued a first-instance verdict on a case of smuggling nine-valent cervical cancer vaccine. The defendant Xu Moli and other four people bought vaccines from Hong Kong at a low price and smuggled them to Shenzhen, and then sold them to various places. Four people smuggled 2,824 vaccines, involving nearly 3 million yuan, with a total profit of more than 120,000 yuan.

　　In fact, it is really helpless for people to turn to the yellow cattle to make an appointment and be asked by the hospital to "distribute" the seedlings. The way to make an appointment for HPV vaccines in various places is harsh, and it has been a long time since they were unable to "go ashore" for many years. Zhongxin Jingwei learned that Beijing made an appointment online and by telephone. However, many community hospitals have told Zhongxin Jingwei that the nine-valent HPV vaccine has no seedlings, and I don’t know when it will be available. Some hospitals in Beijing also have household registration restrictions, and people outside the jurisdiction are not allowed to vaccinate.

　　There are also areas such as Shenzhen that decide who can be vaccinated by "shaking the number". Many people have reported to Zhongxin Jingwei that the process of shaking the number is time-consuming and labor-intensive, and the speed of fighting hands is also luck. Many people can’t get it for half a year. Even if they can get it, there is no guarantee that the other two needles can be vaccinated on time, and there may be problems of overage.

　　Why is the nine-valent HPV vaccine still "one vaccine is hard to find"?

　　It is understood that there are currently three kinds of HPV vaccines listed in the world, and the number of HPV virus subtypes is different, including bivalent vaccine, tetravalent vaccine and nonavalent vaccine. Five HPV vaccine products have been approved for marketing in China, including three imported HPV vaccines and two domestic HPV vaccines.

　　In 2006, the world’s first HPV vaccine came out, until 2016, the first HPV vaccine approved for marketing in China — — The bivalent HPV vaccine "sirrah Shi" produced by GlaxoSmithKline has been in a blank period in China for ten years.

　　Luo Ling, the fund manager of Shanghai Congrong Investment Management Co., Ltd., said in an interview with Zhongxin Jingwei that the reason for the current strong demand is that many people have not been vaccinated with HPV before, and the demand has accumulated to be released at this stage. The next 5 to 10 years may be the stage of replanting the stock population, followed by the annual vaccination of the new population.

　　In 2018, the U.S. Merck nine-valent HPV vaccine "Jiadaxiu" was listed in mainland China, and Zhifei Bio became the exclusive agent of Merck HPV vaccine in China. However, up to now, the nine-valent HPV vaccine is still hard to find.

　　Behind the lack of seedlings, there is only one nine-valent vaccine manufacturer in Merck. Recently, Tian Anna, president of Merck China, pointed out in an interview with the media that it takes nearly four years for each dose of HPV vaccine to be produced and applied.

　　However, the supply of nine-valent HPV vaccine has also increased accordingly. Recently, Zhifei Bio said on the interactive platform that in the first quarter of 2022, the number of batches of nine-valent HPV vaccines increased by nearly 280% year-on-year.

　　Wu Tao said that vaccination with HPV vaccine is the best way to prevent HPV infection and cervical cancer, but don’t blindly wait and pursue the most expensive vaccine, but should be protected as soon as possible. If there is no nine-valent HPV vaccine, it is a better choice to vaccinate low-priced HPV vaccine.

　　In addition to the nine-valent HPV vaccine, the four-valent HPV vaccine market is currently in the hands of Merck. It is understood that the whole vaccination cost of tetravalent and nine-valent vaccines is 2394 yuan and 3894 yuan respectively. In the market competition of bivalent vaccine, domestic vaccine also gets a share with its price advantage.

　　In 2020, Wan Tai Bio’s bivalent HPV vaccine "Xinkening" went on the market, and one shot was only 329 yuan. Even if it was inoculated with three shots, it was only 987 yuan, far lower than the 1,740 yuan of the same dose of GlaxoSmithKline "sirrah Shi".

　　As the first domestic HPV vaccine, "Xinkening" adopts the research and development route of Escherichia coli technology, with low cost and high efficiency. According to the 2021 annual report, the biological business income of Wan Tai increased by 144.25%, mainly due to the increase of bivalent HPV vaccine, reagents and active raw materials, and the gross profit margin of vaccine business was as high as 92.55%. In 2021, the sales of bivalent HPV vaccine in Wan Tai exceeded 10 million, and the government procurement accounted for only 1.5%.

　　In March, 2022, watson biological bivalent HPV vaccine "Wozehui" was also approved for listing, and it was officially put on the market at the end of May, taking away part of the biological market in Wan Tai at a lower price.

　　At the end of May this year, the bivalent HPV vaccine of watson biological and Wanbiotai jointly won the bid for the procurement project of Jiangsu provincial government. The total purchase quantity is 32,000 pieces, of which 22,400 pieces were won at the proposed bid price of 246 yuan/piece in watson biological and 329 yuan/piece in Wan Tai Bio, only 9,600 pieces were won.

　　In this regard, Wan Tai Bio said that since its listing, its bivalent HPV vaccine has been mainly supplied to the self-funded market, and the purchase of free voluntary vaccination by local governments for specific age groups is relatively small, which has limited impact on the company’s operating income.

　　However, Wu Tao told Zhongxin Jingwei that there are regional differences in the distribution of cervical cancer in China, mainly concentrated in the central and western regions, and rural areas are highly prevalent in cities. Clinically, patients with advanced cervical cancer are mostly from rural areas. There are hundreds of millions of low-and middle-income women in China, who are concerned about the price of HPV vaccine besides the preventive effect and safety. "For economically underdeveloped people, the price will directly affect the choice of HPV vaccine types."

　　Is it close to relaxing the age limit?

　　On the track of nine-valent HPV vaccine, which is in short supply, there are more and more R&D and production enterprises in China. It is worth noting that some domestic nine-valent vaccines are expanding the age of the experimental population compared with the suitable age of 16 to 26 years approved by Merck nine-valent vaccine in Chinese mainland.

　　This may mean that with the listing of more nine-valent HPV vaccines in the future, not only can the situation of "one vaccine is hard to find" be alleviated, but the waiting school-age women do not have to be anxious because they are over 26 years old.

　　It is understood that Chongqing Bowei Baitai Biopharmaceutical Co., Ltd. (hereinafter referred to as Bowei Bio), Jiangsu Ruike Biotechnology Co., Ltd. (hereinafter referred to as Ruike Bio), Beijing Kangle Guardian Biotechnology Co., Ltd. and Wan Tai Bio’s nine-valent HPV vaccine have all entered the third clinical stage.

　　Wan Tai Bio started the Phase III clinical trial in September 2020. At that time, the company said that the phase III clinical trial of the nine-valent vaccine was aimed at evaluating the effectiveness and safety of the vaccine in female healthy volunteers aged 18-45. However, as early as 2020, Wan Tai Bio said that the nine-valent vaccine is not expected to be listed within three years according to clinical experience.

　　According to the information of National Medical Products Administration Drug Evaluation Center, the phase III clinical trial of nine-valent vaccine announced by Bowei Bio in 2020 also aims to evaluate the immunogenicity and safety of HPV vaccine among women aged 20-45 in China. Phase III clinical trial was completed in September 2021.

　　In June, 2021, Ruike Bio announced the effectiveness and safety of its nine-valent vaccine in the phase III clinical trial of healthy women, one of the purposes of which was to evaluate the safety and immunogenicity of three doses inoculated in healthy women aged 9-17, 16-26 and 18-45. However, the company did not disclose the completion date of the test.

　　Tao Lina, a vaccine expert, said in an interview with Zhongxin Jingwei that the duration of the third phase clinical trial needs to refer to the sample size: the larger the sample size and the higher the cost, the shorter the observation time; The smaller the sample size, the longer the observation time. You can’t have both fish and bear’s paw, with a large sample size and high investment. It will take one or two years to observe the third-phase clinical trial before you can see the significant difference between the vaccine group and the placebo group. The sample size is small, and it may take more than five or six years to get the difference of incidence and summarize it. It will take at least 2 to 6 years from the start of the third phase clinical trial of domestic HPV vaccine to the approval and listing.

　　Wu Tao told Zhongxin Jingwei that in 2019, Merck launched the third phase clinical trial of nine-valent HPV vaccine in China, bridging the immunogenicity and immune persistence test. The observation period is five years, that is, the earliest nine-valent HPV vaccine in China may relax the age limit to 45-year-old women by 2024. Men’s enrollment is also under way. However, if men in China want to get the nine-valent vaccine, they have to wait five years at the earliest.

　　However, Taulina also pointed out that relaxing to the age of 45 also means that more people are snapping up the nine-valent vaccine, which is still difficult to alleviate the situation of "one needle is hard to find" and even more intense. (Zhongxin Jingwei APP)

　　(The opinions in this article are for reference only, and do not constitute investment advice. Investment is risky, so you should be cautious when entering the market. )

Announcement No.1 of the National Health and Wellness Commission： Revealing important information about the prevention and control of ＂novel coronavirus＂

　　CCTV News:

January 20 th

The National Health and Wellness Commission issued Announcement No.1.

Include pneumonia infected in novel coronavirus.

Class B infectious diseases stipulated in the Law of People’s Republic of China (PRC) on the Prevention and Control of Infectious Diseases.

And take measures to prevent and control Class A infectious diseases.

Include pneumonia infected in novel coronavirus.

Management of Quarantine Infectious Diseases as stipulated in the Frontier Health and Quarantine Law of People’s Republic of China (PRC)

　

our countryClass a infectious diseasesThere are only two kinds: plague and cholera.

　　beforeIncorporate into Class B infectious diseases and adopt Class A management.There are:

Infectious atypical pneumonia (SARS)

Pulmonary anthrax in anthrax

Human infection with highly pathogenic avian influenza

　　Answering Bai Yansong’s Eight Questions Zhong Nanshan put forward three "keys"

　　Prevention, don’t go to Wuhan without special circumstances, this is very important.

　　Wearing a mask is still useful. Actually, you don’t have to wear N95.

　　Early detection and early treatment should prevent transmission and prevent the emergence of "super communicators".

　　[Name card] Zhong Nanshan, head of the high-level expert group of the National Health and Wellness Commission, academician of the China Academy of Engineering, national clinical research expert on respiratory diseases, and a leading figure in the fight against atypical pneumonia in China in 2003.

　　Summary of some Q&A records:

　　Bai Yansong: How can you tell it’s from person to person?

　　Zhong Nanshan: According to the current data, it must have been passed down from person to person. In Wu Hanyou, two patients in Guangdong have never been to Wuhan, but after their families went to Wuhan, they were infected with novel coronavirus, so now they can.There must be a phenomenon of human transmission..

　　Bai Yansong: What should we do from the perspective of medical experts, including the whole medical system? How should ordinary people guard against it?

　　Zhong Nanshan: The key points,One is prevention. Don’t go to Wuhan without special circumstances. This is very important.. If you feel sick or catch a cold, you should go to the local fever clinic and check if necessary. Wear a mask if you are uncomfortable.Wearing a mask is still useful. Actually, you don’t have to wear N95.. Because these viruses do not exist alone, they often exist in droplets. General surgical masks can still block most of them, and wearing masks is still useful.

　　Bai Yansong: What symptoms do ordinary people have to go to the hospital for treatment? Is it a fever?

　　Zhong Nanshan: Because there are more flu in winter, it is not enough to have a fever. One isI have been to Wuhan or there are people from Wuhan at home.This is a premise. Besides, I have a fever, so I should be on my guard.You must go to the fever clinic. At the same time, do nucleic acid testing when necessary..

　　Other important information:

　　Novel coronavirus’s infection has just started and is climbing at the same time, so compared with SARS at that time, it is not so infectious and toxic.

　　The current mortality rate cannot be comprehensive, and I am afraid it depends on the development of the disease. We should be vigilant on this issue.

　　Preliminary epidemiological analysis shows that it is actually transmitted to people through wild animals, which is quite possible. But there is still the phenomenon of human-to-human transmission, which is the time for us to be vigilant.

　　From all aspects of epidemiological investigation, it is more likely that the virus comes from a wild animal, such as bamboo rats and badgers.

　　There is no specific medicine in novel coronavirus at present, but some animal experiments and observations are being carried out now, so scientific research should keep up. During the Spring Festival, it is estimated that the number of sick people will increase, so it is necessary to prevent transmission and prevent the emergence of "super communicators".

　　On the afternoon of 20th, in response to the prevention and control of "pneumonia epidemic in novel coronavirus", Academician Zhong Nanshan, the head of the high-level expert group of the National Health and Wellness Commission, and others answered a reporter’s question, saying that "super communicators" had not appeared yet, and prevention and control in advance was effective.

　　Virologists: The key point should be to prevent the emergence of "super communicators"

　　Zhong Nanshan: At present, there is no "super-disseminator" in the SARS epidemic 17 years ago. Timely isolation of suspicious patients and close contacts can effectively prevent the spread of the epidemic.

　　Guan Yi: After a period of development, the ability to spread the virus will be improved. At a certain level, some special cases will appear in the crowd, and a large number of viruses will be carried, forming a "super communicator". We should find advanced communicators and super communicators as soon as possible, and especially try to prevent the emergence of super communicators.

　　On January 21st, "News 1+1" continued to connect with Zhou Xianwang, Mayor of Wuhan, Gao Zhancheng, a member of the expert group of the National Health and Wellness Commission, and Wang Bin, deputy director of the CDC of the National Health and Wellness Commission, to answer your questions.

　　Incubation period of virus: the average is about 7 days, and the longest is 12 days

　　Gao Zhancheng: In 2003, it will take about half a year to locate the SARS virus. existNovel coronavirus will be confirmed within two weeks.This provides scientific basis and guidance for the research and development of antiviral drugs and vaccines.

　　Gao Zhancheng: Judging from the existing cases, (incubation period of the virus)The average is about 7 days, ranging from 2 to 3 days short to 12 days long..

　　How to distinguish the common cold from novel coronavirus infection, and under what circumstances do you need to see a doctor?

　　Gao Zhancheng: According to the existing cases, the main symptoms are fever, low fever or even high fever; Mainly dry cough; Shortness of breath and chest tightness after three or five days; Some patients will have symptoms of respiratory failure and shock. Remind everyone,Anyone who has fever symptoms should seek medical attention in time, especially those who have been exposed to cases, and seek medical attention as soon as possible..

　　[popular science connection]

　　Enough science: fever, cough to the hospital? Don’t worry yet! Read these three before you act.

　　Enough science: by the way, is it useful to wear a mask? Everything I want to know about novel coronavirus is here.

　　Popular science enough: Will novel coronavirus bats "lie" this time?

　　(Source: official website of National Health and Wellness Commission, official website of Health Emergency Office, news 1+1, etc.)

Ningbo eπ 008 price reduction is coming, the highest profit 28,000! Only this time

[Autohome Ningbo Discount Promotion Channel] Currently, preferential promotions in Ningbo are underway, with a discount of up to 28,000 yuan and a minimum starting price of 188,600 yuan. For more preferential information, consumers can click "Check Car Price" in the quotation form to strive for higher discounts.

宁波eπ008降价来袭，最高让利2.8万！仅此一次

eπ008采用极具辨识度的前脸设计，搭配独特的进气格栅，展现出时尚而动感的风格。车身线条流畅，整体造型兼具现代感与科技感，令人眼前一亮。

eπ008凭借其5002*1972*1732mm的长宽高尺寸和3025mm的轴距，展现出宽敞舒适的内部空间。车身线条流畅，搭配265/45 R21的轮胎规格，进一步提升了车辆的整体视觉效果。轮圈设计独具匠心，彰显了eπ008的时尚与运动风格。

宁波eπ008降价来袭，最高让利2.8万！仅此一次

eπ008的内饰设计以简约现代风格为主，注重人性化与科技感的融合。皮质方向盘不仅手感舒适，还支持手动上下和前后调节，方便不同身高的驾驶者找到最佳握持位置。中控台配备了一块15.6英寸的高清触控屏幕，内置的多媒体系统、导航、电话和空调功能均支持语音识别控制，为驾驶者提供便捷的操作体验。前后排均设有USB和Type-C接口，满足不同设备的充电需求，前排还配备了无线充电功能。座椅采用高品质仿皮材质，主副驾驶座椅具备加热、通风功能，并且驾驶位还配备头枕扬声器。此外，eπ008还提供了电动座椅记忆功能，驾驶者和副驾驶位均可设置并记忆个性化坐姿，后排座椅同样支持多向调节和比例放倒，为乘客提供灵活多变的乘坐空间。

宁波eπ008降价来袭，最高让利2.8万！仅此一次

eπ008搭载了一台高效的电动机，最大功率达到200kW，峰值扭矩为340N·m，提供了强劲的动力输出和平顺的驾驶体验。

汽车之家车主对eπ008的外观设计赞不绝口，他选择的向阳金外漆沉稳而高级，黑色漆面虽然也很出色，但考虑到清洁问题，他最终选择了向阳金，并且在购车时还享受了1500元的优惠，他认为这笔交易非常划算。

Qingdao Lexus RX is being discounted, the highest profit 30,000! Great discount today

[Autohome Qingdao Promotion Channel] brings you timely automotive market trends. At present, the high-profile luxury SUV is in the midst of a high-profile promotion. Consumers in Qingdao are fortunate to enjoy this generous offer, with a maximum discount of up to an astonishing 30,000 yuan. The starting price has been adjusted to a more competitive 375,000 yuan. This discount range brings real benefits to consumers. For more details, or to get the best car purchase price, don’t miss the important part of clicking "Check the car price" in the quotation form, let’s seize this rare car purchase opportunity together.

青岛雷克萨斯RX正在优惠，最高让利3万！今日钜惠

The exterior design of the Lexus RX reflects the perfect blend of elegance and power. On the front face, it features the iconic spindle-shaped air intake grille, paired with sharp LED headlights, to create a unique identity. The body lines are smooth and dynamic, outlining a powerful silhouette. The overall style is elegant and sporty, showing Lexus’s meticulous carving of luxury and practicality.

青岛雷克萨斯RX正在优惠，最高让利3万！今日钜惠

With its elegant body proportions and exquisite side design, the Lexus RX shows the unique charm of a luxury SUV. In terms of body size, its length * width * height are 4890mm*1920mm*1695mm, and the wheelbase reaches 2850mm, ensuring a spacious space for passengers. It is worth noting that the RX is equipped with 19-inch wheels, and the tire specification is 235/60 R19. The proportion of the tire and the body is coordinated, which not only enhances the driving stability, but also perfectly integrates with the side lines, highlighting Lexus’ consistent pursuit of detail and sporty sense.

青岛雷克萨斯RX正在优惠，最高让利3万！今日钜惠

The interior design of the Lexus RX highlights the luxury and refined quality. In the cockpit, the steering wheel is made of leather, which is not only delicate to the touch, but also supports electric up and down + front and rear adjustment to ensure the comfort and convenience of the driver. On the center console, a 9.8-inch high definition central control screen stands, integrating multimedia system, navigation, telephone and air conditioning control, providing the driver with an intuitive operation interface. As for the seats, whether it is the main driver or the passenger seat, they are made of imitation leather, providing front and rear adjustment, backrest adjustment and multi-directional waist support, providing passengers with an excellent riding experience. Both the front and rear rows are equipped with USB and Type-C interfaces to meet the diverse needs of passengers during the journey. The overall interior design takes into account both practicality and luxury, creating a spacious and comfortable interior environment.

青岛雷克萨斯RX正在优惠，最高让利3万！今日钜惠

The Lexus RX is powered by a 2.5L four-cylinder engine capable of delivering 139 kilowatts of maximum power and 241 Nm of peak torque. It is paired with an advanced E-CVT continuously variable transmission, ensuring a smooth driving experience and fuel economy.

Summarizing the owner’s evaluation, the Lexus RX attracted his attention with its luxurious and stable exterior design and unique front face. The body’s proportions and smooth lines make the RX highly recognizable when driving on the road. This feature undoubtedly strengthens the position of this luxury SUV in the hearts of consumers, and fully reflects Lexus’s insistence on detail and quality.

How strong is the Wuling Hongguang S3？ The debut of the new car is exciting

The mainstream car has a moderate size and reasonable price, which is also a major feature of it, so it is loved and chosen by many families. For example, this car is often mentioned as a space issue. As for the outstanding performance of this car, please take a look.

Take a look at the appearance of the Wuling Hongguang S3 first. The front of the Wuling Hongguang S3 gives people a very clean feeling and looks very sharp. Coupled with the fashionable and generous headlights, the overall look is very fashionable and atmospheric. The car is equipped with front fog lights, etc. Come to the side of the car, the body size of the car is 4655MM*1735MM*1790MM, the car adopts domineering and stylish lines, and the side gives people a very eye-catching feeling. With large-sized and thick-walled tires, it leaves a very deep feeling. In terms of rear design, the Wuling Hongguang S3 has a rustic rear line, and the tail lights show a soft design style. Coupled with the unique exhaust pipe, it is still relatively cold overall.

Sitting in the car, the interior of the Wuling Hongguang S3 looks deep and elegant, which is easy to impress the hearts of young consumers. The steering wheel of the car is well designed, made of plastic material, and the feel is good. From the perspective of the central control, the car trim has a cold touch LCD central control screen, which impresses the interior style. The overall design of the central control is remarkable. The interior feels good. Let’s take a look at the dashboard and seats, which create a more sporty atmosphere. The car uses imitation leather seats, which are wide and thick, further improving the comfort of the driver and occupant.

Wuling Hongguang S3 is matched with a manual (MT) gearbox, with a maximum power of 108KW and a maximum torque of 250N.m, providing good power performance.

Next, take a look at the configuration. The Wuling Hongguang S3 is equipped with a rear center armrest, original interconnection/mapping, Bluetooth/WIFI connection, sun visor makeup mirror, USB interface, and other configurations.

I wonder if you are excited about the car introduced today? If you are also concerned, you might as well experience it.

Meizu (meizu) mobile phone MEIZU 21 5G mobile phone 12GB + 256GB smart purple, how much is the Snapdragon 8Gen3？

In terms of appearance design, it adopts the design of straight plate and arc edge frame, and provides four color schemes of Ruiyi Blue, Unbounded Black, Meizu White and Smart Purple in the color scheme. The whole machine is 7.9mm thick and weighs 198g. In terms of screen, it is equipped with a 6.55-inch 120Hz AMOLED screen, ultra-narrow four equilateral, the frame is only 1.74mm, supports DCI-P3 wide color gamut, 1800nit peak brightness, 1500Hz instantaneous sampling rate and 1920Hz PWM high frequency dimming, and passes SGS low blue light eye protection and mLight 10,000-level dimming. In terms of performance, it is equipped with the third-generation Snapdragon 8 processor and adopts TSMC 4nm process. In terms of storage, it provides 8GB + 256GB, 12GB + 256GB, 12GB + 512GB optional. In terms of heat dissipation, it adopts a 37345mm2 super-large area heat dissipation system and a 4045mm2VC liquid-cooled heat dissipation plate, which dissipates heat faster and more efficiently. The exclusive "Ice World" cooling technology is blessed, and the game experience is further improved. In terms of battery life, it is equipped with a 4800mAh large battery and supports 80W fast charging. In terms of imaging, the front Samsung 32MP lens, the rear 200MP main camera (supports OIS optical anti-shake) + 12MP ultra-wide-angle lens + 5MP depth of field lens. In other aspects, it brings a richer Aicy smart ring to provide more interactivity. Supports ultrasonic fingerprint recognition and supports wet hand unlocking. Equipped with the sixth generation master-level "dual" and ultra-linear speakers, it is the first mobile phone to pass the QQ music "premium product certification" panoramic sound playback. Equipped with a horizontal linear motor, the vibration feedback is more obvious. Adopting a new antenna architecture, the WiFi signal is greatly improved; running the Flyme 10.5 system, the use is more stable and smooth, and the interaction is better with intelligence.

Hong Jinbao’s ＂thin and disembodied＂ cheeks are sunken, and he has lost more than 25 kilograms. Now he can only travel in a wheelchair

Dear readers, welcome to stay tuned for updates from Mok. Today we will introduce you to a former kung fu superstar, an actor who rose to prominence in the golden age of Hong Kong cinema. He is Samuel Hung.

It is hard to believe that he once weighed more than 100 kilograms. However, a photo from 2020 is eye-popping. His face is clear-cut, and there is no fat on his neck. Only skin is left. This slimming mystery has attracted widespread attention.

But what is even more worrying is that in recent years, photos taken by netizens show that Hong Jinbao has had to rely on a wheelchair to go out.

This has sparked speculation about what made the former kung fu superstar so different. Some speculate that he may be sick, but what exactly does it take to make someone lose more than 25kg in just one year?

Mr. Hung was a shining star of the golden age of Hong Kong cinema in the 1980s. He helped bring Hong Kong cinema to its peak with kung fu stars such as Jackie Chan and Jet Li. His family background is also unusual. He was born into a film family. His grandfather Hong Ji and grandmother Qian Siying both left a strong mark on the history of Chinese cinema. This family background undoubtedly laid a solid foundation for Hong Jinbao’s acting career.

Hong Jinbao has been passionate about filming and kung fu since childhood. As a child, he entered the Peking Opera class of the China Academy of Drama to study. Among his classmates were many later kung fu superstars, such as Jackie Chan and Yuan Biao. And Hong Jinbao, as the oldest one, became the first person to set foot in the entertainment industry. At the age of 12, he entered the film industry as a child star. He began to participate in martial arts dramas at the age of 18. In his 20s, he has become a leading actor. Such achievements are no easy feat for a young person.

However, Samuel Hung’s career has not been smooth sailing. He once challenged Bruce Lee, but before he could stretch out his foot, Bruce Lee’s leg was already resting on his face.

The unexpected death of Bruce Lee scattered the martial artists who had followed him. For his own career, Hong Jinbao established the Hong Family Class. This group has trained many famous actors, including Jackie Chan, Afternoon Horse, Qian Jiale, etc. The most famous of them is Lin Zhengying. He became famous with "Mr. Zombie", and Hong Family Class also officially entered the Hong Kong film industry.

However, time is not forgiving. With the rise of the Internet, old-fashioned Hong Kong films have gradually been phased out by the times, and Hong Jinbao has gradually faded from the public eye. Although he directed and starred in a film "My Agent Grandpa" in 2016, his results are far worse than that of the year. He admits that he has not kept up with the changes of the times and feels like an old man who has been abandoned by the times.

In 2017, Samuel Hung underwent knee surgery. His knee problems have long been bothering him. After the surgery, the doctor advised him to lose about 25 kilograms of weight. Therefore, we have seen many photos of him on crutches or in a wheelchair in recent years. Samuel Hung follows the doctor’s advice very well. In general, he uses a wheelchair, and only in formal settings does he use crutches.

Photographs from 2020 show that Samuel Hung’s weight loss results are quite remarkable. He looks refreshed and in a good mood. However, in the past two years, he seems to have gained weight again. Some people have begun to wonder whether his illness caused the sharp weight loss. After all, a person’s sudden weight loss in a short period of time is often a sign of physical problems.

In fact, it was not out of the blue that Samuel Hung began to consciously control his weight after knee surgery. However, for the former kung fu superstar, his body has suffered too much damage, which may be the price of time.

Samuel Hung, a former screen star, is now old and away from the big screen. However, his classics will live on forever, and we hope he can take care of his body and have a wonderful time

Old age.

At this prime age, Samuel Hung may no longer be active in front of the screen, but his brilliance still illuminates the film industry. Countless audiences still miss his classic martial arts scenes and funny performances.

His works have long transcended the time of generations of audiences, becoming immortal classics that will forever remain in the pages of film history.

We cannot predict the future of Samuel Hung. Perhaps he will continue to be active in the entertainment industry in other ways, or he may choose to enjoy a peaceful retirement. Either way, his contributions and legends will always be remembered, and his story will continue to inspire a new generation of actors and audiences.

In the end, Samuel Hung’s experience tells us that time leaves its mark on everyone, but no matter what, we should cherish our health, fight against adversity, and embrace every stage of life. Samuel Hung was the "flexible fat man", and now he is the eternal kung fu superstar in our hearts.

Responsible editor:

Welfare+guarantee, ask the new M7 new gameplay to promote the big decision. In 45 days, 70,000 sets have been broken!

There are still two months to the end of the year, and the automobile market is surging. In order to occupy the automobile market, major automobile brands have come up with unique tricks. Among them, the unique marketing strategy of the new M7 in Wenjie has gained widespread attention in the market. It is understood that Huawei not only provided 30,000 yuan worth of rights and interests for the new M7, but also promised to delay the delivery of subsidies for 200 yuan/day, providing consumers with a car purchase experience of "having benefits on the top and being guaranteed on the bottom", creating a record ceiling of 70,000 units in 45 days.

Different from the strategy of focusing on "promotion" when new cars of other automobile brands go on the market, Huawei has taken a different approach to stand on the side of consumers, dig deep into consumers’ needs, and introduce rights and protection at the same time. Specifically, the big rights and interests of this new car include:

(Time: 10.8-10.31)

(1) enjoy 5,000 yuan to deduct 8,000 yuan, and reduce the final payment;

(2) a gift of 12,000 yuan worth of interior and exterior decoration matching gold;

③ Enjoy the matching rights worth 15,000 yuan (as described below);

Max smart driving edition users can deduct the optional ADS2.0 urban navigation NCA function by equal amount;

Plus rear-drive users can choose and install a technology enjoyment package worth 15,000 yuan in equal amount;

Users of all models can also choose a combination of rights and interests with a value of 15,000 yuan (21-inch wheels with a value of 10,000 yuan and one of the original aftermarket products).

In order to make consumers worry-free about buying a car, Huawei has also made a care plan for the new M7. According to this plan, new M7 users who have completed the big payment before November 30, 2023, the order status on AITO App starts from the date of "delivery plan confirmed" to the date of "vehicle has arrived at the store". If the waiting period in the table below is exceeded, they will receive the cash subsidy for car pick-up care according to the number of days (vehicle arrival date-delivery plan confirmed date-waiting period). The standard of overdue subsidy is 200 yuan/day, up to 10,000 yuan.

On the basis of marketing strategy innovation, Yu Chengdong, managing director of Huawei, CEO of BG, and chairman of BU, a smart car solution, personally promised that Celeste Smart Factory is working overtime to ensure market supply demand. At the same time, the investment in the supply chain has exceeded 1 billion yuan, and new production shifts are running around the clock 22 hours a day, making every effort to ensure delivery. This wave of operations makes consumers satisfied with Huawei’s strength and commitment.

The new M7 in Wenjie broke through the large quota of 50,000 orders in 25 days, reaching 60,000 orders a month, and the quota has exceeded 70,000 units in 45 days! Such achievements are remarkable. Of course, the new M7 has achieved such good results, not only relying on welfare and rights, but also relying on Huawei’s strong product strength and user orientation.

Empowered by Huawei, the new M7 intelligent driving field in the world is far ahead. At present, the new M7 intelligent driving version of Wenjie has completed the OTA upgrade, and supports the functions of high-speed NCA and urban LCC. On high-speed and elevated roads, vehicles can follow the navigation to their destinations, and consciously identify the signal lights to assist in controlling normal driving, intelligent lane change, intelligent speed limit, etc., which greatly liberates drivers from manipulating characters. It can also show its talents in urban roads, cruise at a fixed speed, follow the car, cross corners, etc. in the traffic flow, and it can also realize automatic avoidance in and out of the lane, greatly improving driving safety and happiness. It is worth mentioning that Huawei also uses technology to make parking more self-free. Because of the launch of the custom parking function, users can drag and drop vehicle icons on the ground where parking is allowed but not marked. A temporary parking space is supported with the narrowest width of +0.4m, and there is no need to ask an old driver for parking.

Not only that, but the new M7 in space and interior also shows amazing strength. In terms of interior space design, the new M7 in Wenjie has gained more effective interior space with a smaller "pool" through excellent design and layout optimization, with a "room occupancy rate" of 66.3%, leading the same class, and both front and rear rows can get a very spacious and comfortable experience. Moreover, in order to further improve the experience of drivers and passengers, the seats of the new car are designed with 10 layers of comfort lamination, with a total foam thickness of 100mm, and four seats are equipped with ventilation, heating and massage functions as standard, which can bring drivers and passengers a comfortable experience like first class. In addition, thanks to Huawei’s strong technical strength, the car’s Xiaoyi intelligent assistant can greatly liberate the user’s hands, and the double-row nap function of the main and auxiliary drivers can be turned on through voice, bringing more comfort, intelligence and fun to the user’s travel experience. In addition, the new M7 also provides a six-seat layout, giving consumers more car choices.

From the perspective of users, Huawei not only provides high-quality products and services, but also cares about the needs and rights of consumers. The new M7 in the world has won the favor of consumers through Huawei’s unique marketing strategy and caring plan, and soon became a hot model in the market after listing. If you have a car purchase plan recently, you may wish to take a look at the new M7 in the world. Now you can enjoy the rights and protection of buying a car, so act quickly!

Warm reminder! It is related to the examination of motor vehicle drivers in rainy and snowy weather.

Jining News Network News On February 1st, Jining Vehicle Management Office issued "Warm Tips on Motorists’ Examination in Rain and Snow", as follows:

According to the meteorological department, from February 2 to February 5, there were still rain, snow and strong winds in Jining. In view of the snow and ice on the road, dmv, the Municipal Public Security Bureau, has launched an emergency plan for bad weather, timely investigated the road conditions of the examination room, and made a good job of snow removal and ice melting to meet the test requirements as much as possible.

However, it is still uncertain whether the automobile subject II (venue) and subject III (road test) can be organized normally by then. If, after work, the examination room still does not meet the normal examination conditions, the vehicle management office will release the news at the first time through the "Jining Vehicle Management Office" WeChat WeChat official account and the driving school work WeChat group, and notify the candidates in time, and the vehicle management office will cancel the examination in a unified manner; If the examination room has the examination conditions, and remote candidates can’t get to the examination room to take the exam due to extreme weather, the vehicle management office will cancel the exam the next day. The above cancelled exams will not be counted as the number of exams, and no fees will be charged, which will not affect the candidates’ ranking for the next exam. If a candidate’s driving certificate is about to expire or under other special circumstances, please report it to the vehicle management office in time through the traffic control 12123 voice service hotline or the driving school where you are located, and we will serve you wholeheartedly. I apologize for the inconvenience caused by the delay in the examination process due to the weather. Thank you for your understanding and support of the traffic police vehicle management work!

Please pay attention to safety when traveling in rainy and snowy weather! As the Spring Festival approaches, I sincerely wish you all good luck, peace, joy and happiness in the Year of the Dragon!

Tel: 0537-12123

Jining Bureau of Public Security dmv

February 1, 2024

Reporting/feedback